High-throughput biochemical assays targeting a vital viral protein identified one molecule out of more than 13,000 with promising antiviral activity against SARS-CoV-2.

Understanding lipid composition of ant fungal gardens provides new knowledge on interkingdom communications band and also advances toward the development of microbial systems that can produce valuable compounds from plant biomass.

Night shift work disrupts the natural 24-hour rhythms in the activity of certain cancer-related genes, making workers more vulnerable to damage to their DNA.

A new review paper led by senior research scientist Chun-Long Chen and featured on the cover of Accounts of Chemical Research summarizes advances by PNNL scientists in developing sequence-defined peptoids.

The article, “Nanoscale observations of Fe(II)-induced ferrihydrite transformation,” was selected for articles published in 2020.

PNNL researchers are examining the volatile radioisotope iodine as it evolves in the atmosphere and as it lands on a filtering surface.

PNNL computational biologists, structural biologists, and analytical chemists are using their expertise to safely accelerate the design step of the COVID-19 drug discovery process.

In a new video series, PNNL is highlighting six scientific and technical experts in the national security domain throughout the fall. Each was promoted to scientist and engineer Level 5, one of PNNL’s most senior research roles.

A zoonotic coronavirus known as SADS-CoV that has killed many pigs has the ability to infect human cells, surprising scientists.

Pacific Northwest National Laboratory (PNNL) researchers pioneer a new tool to represent cellular response to viral infection.

Researchers trained deep neural networks to accurately predict microbial interactions captured by fluorescence microscopy.

By studying discrete functional components of the soil microbiome at high resolution, researchers obtained a more complete picture of soil diversity compared to analysis of the entire soil community.

Six months into a pandemic that has claimed more than 570,000 lives worldwide, scores of PNNL scientists are engaged in dozens of projects in the fight against COVID-19.

Researchers have developed a new technique to visualize the activity and distribution of enzymes that mobilize phosphate around plant roots.

Accurate identification of metabolites, and other small chemicals, in biological and environmental samples has historically fallen short when using traditional methods.

A new study using proteogenomics to compare cancerous tissue with normal fallopian tube samples advances insights about the molecular machinery that underlies ovarian cancer.

PNNL researchers and professional staff led discussions ranging from biothreats and climate change to science careers at the 2020 annual meeting of the American Association for the Advancement of Science, held this year in Seattle.

The researchers treated human pancreatic islets with substances produced by the body and thought to be involved in the diabetes disease process.

When two powerful earthquakes rocked southern California earlier this month, officials’ attention focused, understandably, on safety. How many people were injured? Were buildings up to code? How good are we at predicting earthquakes?

Patricia Huestis, a collaborator in the Interfacial Dynamics in Radioactive Environments and Materials (IDREAM) Energy Frontier Research Center, has been awarded the DOE Office of Science Graduate Student Research (SCGSR) award.