COVID-19 infections at PNNL early in the pandemic were caused by a wide variety of viral sequences, according to a new analysis by Laboratory researchers.

Gosline works to develop computational algorithms that are uniquely targeted for rare disease work by doing foundational research in model system development. This work can be expanded to all model systems in human disease.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.

Staff at PNNL recently completed a report highlighting commercial products enabled through projects funded by the Department of Energy’s Building Technologies Office.

Findings show method to better prepare human lung tissue for study; it represents the latest mass spectrometry-based omics advances.

The Simple Building Calculator, developed at PNNL, meets a need for a quick, interactive, and economic method to evaluate energy use—and potential savings from efficiency measures—in simple commercial buildings.

To thwart pathogens, researchers in the epidemiology field of infectious disease (ID) prediction are continuously trying to forecast when, where, and how an ID event will occur.

Silicone wristbands could be more convenient option for collecting exposure data.

The Department of Energy has issued updated energy conservation standards for manufactured homes. The effort to establish the standards, supported by PNNL, is expected to result in a range of benefits for the manufactured housing sector.

PNNL worked with the Department of Energy on the Commercial Packaged Boiler rule, which will help reduce energy use, enhance the environment, and save dollars.

PNNL scientists have developed a new mass spectrometry method for in-depth analysis of proteins in individual cells.

Proteomics revealed molecular mechanisms by which the drug Verapamil could prolong beta cell function in early-onset type 1 diabetes patients.

Study highlights microbiome’s role in regulating xenobiotic metabolism.

Development of a one-meter path length miniature ion mobility spectrometer based on multilevel structures for lossless ion manipulations.

Researchers characterize protein signatures that indicate Acute Kidney Injury in COVID-19 patients.

Simulations reveal advantages of using new model vs. allometric scaling for risk assessment.

A multi-institutional team has obtained information about nanoscale interactions between the spike protein of the novel coronavirus SARS-CoV-2 and common household inorganic surfaces.

Exposure to polycyclic aromatic hydrocarbons found at Superfund Sites induces enzymes in dose- and time-dependent patterns in mice.

The web-based tool, called PLATIPUS, is publicly available and interacts with publications available in the CovidScholar database.

Modeling study suggests vigorous ventilation can cause spike in viral concentrations