Gosline works to develop computational algorithms that are uniquely targeted for rare disease work by doing foundational research in model system development. This work can be expanded to all model systems in human disease.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.

Findings show method to better prepare human lung tissue for study; it represents the latest mass spectrometry-based omics advances.

Researchers identified a new intermediate phase that forms during the crystallization of hydrated aluminum-containing salts.

To thwart pathogens, researchers in the epidemiology field of infectious disease (ID) prediction are continuously trying to forecast when, where, and how an ID event will occur.

Silicone wristbands could be more convenient option for collecting exposure data.

PNNL research, featured on the cover of two science journals, describes advancements in using Raman spectrometry for Hanford Site nuclear waste remediation.

Combining multiple experimental techniques allowed researchers to observe the early stages of oxidation in a model material.

PNNL scientists developed new capabilities to study materials under extreme conditions.

PNNL scientists have developed a new mass spectrometry method for in-depth analysis of proteins in individual cells.

Proteomics revealed molecular mechanisms by which the drug Verapamil could prolong beta cell function in early-onset type 1 diabetes patients.

Different sized helium cavities that form after ion irradiation are unevenly distributed in a ductile-phase toughened tungsten composite.

Study highlights microbiome’s role in regulating xenobiotic metabolism.

Development of a one-meter path length miniature ion mobility spectrometer based on multilevel structures for lossless ion manipulations.

IDREAM researchers assess the potential of photon-in/photon-out XFEL techniques to explore early time reaction steps and ultimately improve nuclear waste processing strategies.

Researchers characterize protein signatures that indicate Acute Kidney Injury in COVID-19 patients.

Simulations reveal advantages of using new model vs. allometric scaling for risk assessment.

A multi-institutional team has obtained information about nanoscale interactions between the spike protein of the novel coronavirus SARS-CoV-2 and common household inorganic surfaces.

New PNNL research provides the first direct evidence that amorphous intermediates influence subsequent crystallization outcomes using in situ imaging.

A strengthened softer alloy phase increases the toughness of a tungsten composite material.