A PNNL scientist is studying the structures of the proteins on the surface of the novel coronavirus, using NMR spectroscopy to reveal information about the molecular toolkit that holds the keys to a vaccine or treatment.
Combining its strength in biological sciences and data analytics, researchers at the Department of Energy's PNNL are working to enable a quick response to a biological incident — whether intentional, accidental or natural.
A new study focusing on the proteins involved in endometrial cancer, commonly known as uterine cancer, offers insights about which patients will need aggressive treatment and which won’t.
While it’s one small step forward for mouse research, it’s a big step forward for understanding proteins, the molecular workhorses in biological organisms.
The first phase, which started in 2014, generated foundational data from developing mouse and human lungs, created a web portal for public data sharing, and established a repository of human lung tissues.
When two powerful earthquakes rocked southern California earlier this month, officials’ attention focused, understandably, on safety. How many people were injured? Were buildings up to code? How good are we at predicting earthquakes?
PNNL scientist Wei-Jun Qian and colleagues have contributed to a study that offers clues for delaying or even preventing the autoimmune attack that’s at the core of type-1 diabetes.
PNNL researchers today published a pair of papers, in Cell and in Nature, exploring the effects of the gut microbiome on our health, including autism, brain function, and inflammatory bowel disease.
PNNL researchers have devised a way to measure and distinguish tiny amounts of phosphorylated proteins, an approach that could be used in research to help treat diseases such as diabetes and cancer.
The structure of a fundamental electrical switch in the brain has been revealed, thanks to PNNL researchers working together with counterparts at Oregon Health & Science University (OHSU).
PNNL scientists have taken one of the most in-depth looks ever at the riot of protein activity that underlies colon cancer and have identified potential new molecular targets to try to stop the disease.
One of the most common and deadly complications from a heart attack is kidney failure. New research indicates that a specific protein in the bloodstream created after cardiac arrest may be the culprit...
Our gut’s microbial community is not unlike a country club membership. We know who’s a member, but we may not know how each contributes to the overall function or health of the club....
A detailed analysis of blood samples from Ebola patients in Sierra Leone is providing clues about the progression of the effects of the virus and potential treatment pathways. The findings point to a critical role for a molecular pathway.
Pacific Northwest National Laboratory and Washington State University researchers have developed a novel way to deliver drugs and therapies into cells at the nanoscale without causing toxic effects that have stymied other such efforts.