Integrating experiments and modeling show how a fungal exudate-inspired substrate mixture elicits an emergent growth phenotype and metabolic responses in Pseudomonas putida.

Uncovered how the choice of carbon source influences the stress tolerance, redox balance, and regulatory responses of yeast, which can help provide resilience against scale-up challenges.

Five PNNL innovations earned 2026 R&D 100 Awards for advances in biotechnology, manufacturing, critical minerals, and nuclear security.

Genesis Mission awards to PNNL will advance scientific discovery, next-generation energy systems and advanced manufacturing, among others.

Integrating multiple structural proteomics techniques helps unravel microbial responses to changing environments—key to developing next-generation biotechnology solutions.

Study shows the advantages of top-town proteomics for characterizing histones.

Scientists are optimizing microbes to harvest critical minerals and produce bioproducts using AI and autonomous lab equipment.

Integrating new functions into a genome-scale model enabled researchers to simulate and experimentally validate viral hijacking pathways.

Margaret Cheung elected to premier scientific society.

A microbial community expresses a phenotype of interest ~20 percent higher than the sum of each member species.

Automated liquid handling, combined with data analysis and AI, optimizes microbiological growth conditions at PNNL.

Autonomous science laboratories are taking shape quickly across the PNNL campus.

From exploring the development of transformative materials to strengthening biotechnology, six up-and-coming PNNL scientists were recognized for their scientific vision and prowess.

Pacific Northwest National Laboratory scientists envision new research frontiers at the intersection of biology and AI

Structural proteomics reveal how cyanobacteria adapt to changing light.

Secretary Wright visited PNNL's campus in Richland, Washington, late last year to meet with innovators in chemistry, biology, computing, and more.

Researchers use multiomics to confirm role of lipid synthesis during infection, leading to model of how to restrict virus replication.

McDermott is co-chairing one of only five organized sessions at the annual Pacific Symposium on Biocomputing.

PNNL researchers Daniel Deng and Yehia Ibrahim join the 2025 class of National Academy of Inventors Fellows.

Pioneering autonomous science facility puts a big focus on tiny microbes and AI-driven science.