Data-driven autonomous technology to rapidly design and deliver antiviral interventions targeting SARS-CoV-2 to reduce drug discovery timeline and advance bio preparedness capabilities.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.

Findings show method to better prepare human lung tissue for study; it represents the latest mass spectrometry-based omics advances.

Advancing the science of radiation, especially among students at minority-serving institutions, is the goal of one of the Department of Energy’s newest consortia.

PNNL scientists developed new capabilities to study materials under extreme conditions.

Researchers use machine learning to speed up the analysis of aerosol datasets from mass spectrometry.

PNNL scientists have developed a new mass spectrometry method for in-depth analysis of proteins in individual cells.

Data from increasingly complex mass spectrometry instruments met with adaptable data analysis solution.

Proteomics revealed molecular mechanisms by which the drug Verapamil could prolong beta cell function in early-onset type 1 diabetes patients.

Study highlights microbiome’s role in regulating xenobiotic metabolism.

Development of a one-meter path length miniature ion mobility spectrometer based on multilevel structures for lossless ion manipulations.

Researchers characterize protein signatures that indicate Acute Kidney Injury in COVID-19 patients.

Soil moisture influences both the activity of soil DNA viruses, as well as the composition and abundance of RNA viruses.

PNNL paper in Nuclear Technology journal unveils modeling possibilities for TRISO used fuel, implications for reactor planning, and resulting carbon-free nuclear energy.

Knowing which bacteria in a community are involved with carbon cycling could help scientists predict how microbial carbon storage and release could influence future climate dynamics.

New quantum chemistry pipeline can help predict the effects of bioengineering.

High-throughput biochemical assays targeting a vital viral protein identified one molecule out of more than 13,000 with promising antiviral activity against SARS-CoV-2.

A new article reviews bio-orthogonal click chemistry reagents that can be used as probes to label metabolic pathways in plants and microbes.

Understanding lipid composition of ant fungal gardens provides new knowledge on interkingdom communications band and also advances toward the development of microbial systems that can produce valuable compounds from plant biomass.

Researchers propose and test foundational concepts for the new subdiscipline of “meta-metabolome ecology.”