Data-driven autonomous technology to rapidly design and deliver antiviral interventions targeting SARS-CoV-2 to reduce drug discovery timeline and advance bio preparedness capabilities.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.

Findings show method to better prepare human lung tissue for study; it represents the latest mass spectrometry-based omics advances.

ICON science is a Department of Energy-developed framework to enhance scientific outcomes via more intentional design of research efforts across all domains of science.

Researchers use machine learning to speed up the analysis of aerosol datasets from mass spectrometry.

PNNL scientists have developed a new mass spectrometry method for in-depth analysis of proteins in individual cells.

Data from increasingly complex mass spectrometry instruments met with adaptable data analysis solution.

Proteomics revealed molecular mechanisms by which the drug Verapamil could prolong beta cell function in early-onset type 1 diabetes patients.

Study highlights microbiome’s role in regulating xenobiotic metabolism.

Development of a one-meter path length miniature ion mobility spectrometer based on multilevel structures for lossless ion manipulations.

Researchers characterize protein signatures that indicate Acute Kidney Injury in COVID-19 patients.

Soil moisture influences both the activity of soil DNA viruses, as well as the composition and abundance of RNA viruses.

A new microbial community model reveals previous exposure to hydrologic variation influences a species’ specialized biogeochemical functions.

Detailed characterization of molecules in, under, and along the Columbia River reveal potential mechanisms for biogeochemical cycling.

Integrating hydrogeology and biogeochemistry are required to model the dynamics of geochemical processes occurring in river corridor zones where groundwater and surface water mix.

Theoretical analysis reveals flow variations that happen over longer time periods affect a plume’s spread and center of mass.

Knowing which bacteria in a community are involved with carbon cycling could help scientists predict how microbial carbon storage and release could influence future climate dynamics.

New quantum chemistry pipeline can help predict the effects of bioengineering.

High-throughput biochemical assays targeting a vital viral protein identified one molecule out of more than 13,000 with promising antiviral activity against SARS-CoV-2.

Principles derived from coastal wetlands to describe wetland channel cross-sections were applicable to the Columbia River estuary, but not the tidal river.