Researchers developed a robust, cost-effective, and easy-to-use cap-based technique for spatial proteome mapping, addressing the lack of accessible proteomics technologies for studying tissue heterogeneity and microenvironments.

CACTUS provides AI-powered cheminformatics for autonomous science.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

Early life exposure to polycyclic aromatic hydrocarbons (PAHs), found in smoke, has been linked to developmental problems. To study the impacts of these pollutants, PAH metabolism in infants and adults were compared.

PMedIC, the PNNL and OHSU joint research collaboration, contributes to student success and impact in biomedicine.

The Department of Energy Office of Nuclear Energy acting assistant secretary makes his first visit to a national laboratory in his new role, touring PNNL's Radiochemical Processing Laboratory.

PNNL researchers review ceramic-metal composite technology for immobilizing radioactive wastes from nuclear reactors, including advanced reactors.

Data reveals mechanisms in our bodies that can help us fight viral pathogenesis.

PNNL researchers use chemometric analysis to model chemistry in molten salt.

Pacific Northwest may face increase in summer heat-dome-like stationary waves.

Resolving how nanoparticles come together is important for industry and environmental remediation. New work predicts nanoparticle aggregation behavior across a wide range of scales for the first time.

Scientists screen for nanobodies that recognize wild type and mutant functional proteins to develop a framework to disrupt protein interactions that can cause disease.

A poem inspired by radioactive tank waste—“Can a Scientist Dream it Alone?”—was awarded first place in the Department of Energy’s Poetry of Science Art Contest.

COVID-19 infections at PNNL early in the pandemic were caused by a wide variety of viral sequences, according to a new analysis by Laboratory researchers.

Irradiated boehmite nanoplatelets form smaller aggregates and have a rougher surface than non-irradiated platelets.

Gosline works to develop computational algorithms that are uniquely targeted for rare disease work by doing foundational research in model system development. This work can be expanded to all model systems in human disease.

Hydrogen bonding and proton transfer control the identity and reactivity of molecules in highly concentrated and alkaline aluminate solutions.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.

Findings show method to better prepare human lung tissue for study; it represents the latest mass spectrometry-based omics advances.

Researchers identified a new intermediate phase that forms during the crystallization of hydrated aluminum-containing salts.