Skip to main content

PNNL

  • About
  • News & Media
  • Careers
  • Events
  • Research
    • Scientific Discovery
      • Autonomous Science
      • Biology
        • Chemical Biology
        • Computational Biology
        • Ecosystem Science
        • Human Health
          • Cancer Biology
          • Exposure Science & Pathogen Biology
        • Integrative Omics
          • Advanced Metabolomics
          • Chemical Biology
          • Mass Spectrometry-Based Measurement Technologies
          • Spatial and Single-Cell Proteomics
          • Structural Biology
        • Microbiome Science
          • Biofuels & Bioproducts
          • Human Microbiome
          • Soil Microbiome
          • Synthetic Biology
        • Predictive Phenomics
      • Earth & Coastal Sciences
        • Global Change
        • Atmospheric Science
          • Atmospheric Aerosols
          • Human-Earth System Interactions
          • Modeling Earth Systems
        • Coastal Science
        • Ecosystem Science
        • Subsurface Science
        • Terrestrial Aquatics
      • Materials Sciences
        • Materials in Extreme Environments
        • Nondestructive Examination
        • Precision Materials by Design
        • Science of Interfaces
        • Smart Advanced Manufacturing
          • Cold Spray
          • Friction Stir Welding & Processing
          • ShAPE
      • Nuclear & Particle Physics
        • Dark Matter
        • Neutrino Physics
        • Fusion Energy Science
      • Quantum Information Sciences
      • Chemistry
        • Computational Chemistry
        • Chemical Separations
        • Chemical Physics
        • Catalysis
      • Fusion Energy Science
    • Energy Resiliency
      • Electric Grid Modernization
        • Emergency Response
        • Grid Analytics
          • AGM Program
          • Tools and Capabilities
        • Grid Architecture
        • Grid Cybersecurity
        • Grid Energy Storage
        • Transmission
        • Distribution
      • Energy Efficiency
        • Appliance and Equipment Standards
        • Building Energy Codes
        • Building Technologies
          • Advanced Building Controls
          • Advanced Lighting
          • Building-Grid Integration
        • Commercial Buildings
        • Federal Buildings
          • Federal Performance Optimization
          • Resilience and Security
        • Residential Buildings
          • Building America Solution Center
          • Energy Efficient Technology Integration
          • Home Energy Score
        • Energy Efficient Technology Integration
      • Energy Storage
        • Electrochemical Energy Storage
        • Flexible Loads and Generation
        • Grid Integration, Controls, and Architecture
        • Regulation, Policy, and Valuation
        • Science Supporting Energy Storage
        • Chemical Energy Storage
      • Environmental Management
        • Waste Processing
        • Radiation Measurement
        • Environmental Remediation
      • Fossil Energy
        • Subsurface Energy Systems
        • Advanced Hydrocarbon Conversion
      • Nuclear Energy
        • Fuel Cycle Research
        • Advanced Reactors
        • Reactor Operations
        • Reactor Licensing
        • Nondestructive Examination
      • Renewable Energy
        • Solar Energy
        • Wind Energy
          • Wind Resource Characterization
          • Wildlife and Wind
          • Wind Systems Integration
          • Wind Data Management
          • Distributed Wind
        • Marine Energy
          • Environmental Monitoring for Marine Energy
          • Marine Biofouling and Corrosion
          • Marine Energy Innovation
          • Marine Energy Resource Characterization
          • Testing for Marine Energy
        • Hydropower
          • Environmental Performance of Hydropower
          • Hydropower Cybersecurity and Digitalization
          • Hydropower and the Electric Grid
          • Materials Science for Hydropower
          • Pumped Storage Hydropower
          • Water + Hydropower Planning
        • Grid Integration of Renewable Energy
        • Geothermal Energy
          • Geothermal Materials Research
      • Transportation
        • Bioenergy Technologies
          • Algal Biofuels
          • Aviation Biofuels
          • Waste-to-Energy and Products
        • Hydrogen & Fuel Cells
        • Vehicle Technologies
          • Emission Control
          • Energy-Efficient Mobility Systems
          • Lightweight Materials
          • Vehicle Electrification
          • Vehicle Grid Integration
    • National Security
      • Chemical & Biothreat Signatures
        • Contraband Detection
        • Pathogen Science & Detection
        • Explosives Detection
        • Threat-Agnostic Biodefense
      • Cybersecurity
        • Discovery and Insight
        • Proactive Defense
        • Trusted Systems
      • Nuclear Material Science
      • Nuclear Nonproliferation
        • Radiological & Nuclear Detection
        • Nuclear Forensics
        • Ultra-Sensitive Nuclear Measurements
        • Nuclear Explosion Monitoring
        • Global Nuclear & Radiological Security
      • Stakeholder Engagement
        • Disaster Recovery
        • Global Collaborations
        • Legislative and Regulatory Analysis
        • Technical Training
      • Systems Integration & Deployment
        • Additive Manufacturing
        • Deployed Technologies
        • Rapid Prototyping
        • Systems Engineering
      • Threat Analysis
        • Advanced Wireless Security
          • 5G Security
          • RF Signal Detection & Exploitation
        • Border Security
        • Internet of Things
        • Maritime Security
        • Millimeter Wave
        • Mission Risk and Resilience
    • Data Science & Computing
      • Artificial Intelligence
      • Graph and Data Analytics
      • Computational Mathematics & Statistics
      • Future Computing Technologies
        • Adaptive Autonomous Systems
    • Publications & Reports
    • Featured Research
  • People
    • Inventors
    • Lab Leadership
    • Lab Fellows
    • Staff Accomplishments
  • Partner with PNNL
    • Education
      • Undergraduate Students
      • Graduate Students
      • Post-graduate Students
      • University Faculty
      • University Partnerships
      • K-12 Educators and Students
      • STEM Education
        • STEM Workforce Development
        • STEM Outreach
      • Internships
    • Community
      • Philanthropy
      • Volunteering
    • Industry
      • Why Partner with PNNL
      • Explore Types of Engagement
      • How to Partner with Us
      • Available Technologies
      • Procurement
      • Technology Ombuds
  • Facilities & Centers
    • All Facilities
      • Atmospheric Radiation Measurement User Facility
      • Electricity Infrastructure Operations Center
      • Energy Sciences Center
      • Environmental Molecular Sciences Laboratory
      • Grid Storage Launchpad
      • Institute for Integrated Catalysis
      • Interdiction Technology and Integration Laboratory
      • PNNL Portland Research Center
      • PNNL-Seattle
      • PNNL-Sequim (Marine and Coastal Research)
      • Radiochemical Processing Laboratory
      • Shallow Underground Laboratory

LEarning-Accelerated Domain Science (LEADS) Institute

  • About
  • Research
  • Team
  • Software
  • Publications

Breadcrumb

  1. Home
  2. Projects
  3. LEarning-Accelerated Domain Science (LEADS) Institute

Software

The LEADS team is developing an AI/ML community hub by:

•Establishing a common data format for scientific applications with a focus on foundation models.

•Establishing interoperability policies between codes and models, which avoid conflicts and standardize APIs, especially with respect to the use of external software in other programming languages.

•Focusing on outreach toward the broader SciML community to ensure the approach is beneficial without being restrictive toward uncommon but important edge cases.

•Developing portable ways to test, benchmark, and deploy AI/ML models across Department of Energy Leadership Computing Facilities.

 

Available Software

 

1) NeuroMANCER

PyTorch-based framework for solving parametric constrained optimization problems, physics-informed system identification, and parametric model predictive control

Description

Neural Modules with Adaptive Nonlinear Constraints and Efficient Regularizations (NeuroMANCER) is an open-source differentiable programming library for solving parametric constrained optimization problems, physics-informed system identification, and parametric model-based optimal control. NeuroMANCER is written in PyTorch and allows for systematic integration of machine learning with scientific computing for creating end-to-end differentiable models and algorithms embedded with prior knowledge and physics.

Target audience

Science teams interested in parametric constrained optimization and control.

License: BSD-3-Clause

Additional resources

  •  Repository
  •  Download (PyPI package)
  •  Documentation

 

2) TorchBraid

This package implements a layer-parallel approach to training neural ordinary differential equations (ODEs), and neural networks

Description

Algorithmically multigrid-in-time is used to expose parallelism in the forward and backward propagation phases used to compute the gradient. The neural network interface is build on PyTorch, while the backend uses XBraid (a C library) for multigrid-in-time. TorchBraid uses direct GPU communication when running simulations on GPUs. A CUDA-aware MPI implementation is required for multi-GPU support.

Target audience

Science teams interested layer-parallel approach to training of neural networks.

 License: BSD-3-Clause

 Package links

  • E4S: TORCHBRAID

Additional resources

  •  Repository
  •  Documentation

     

3) GenAI4UQ

A Python package for forward and inverse uncertainty quantification in model calibration, parameter estimation, and ensemble forecasting

Description

GenAI4UQ leverages a generative AI-based conditional modeling framework to address limitations of traditional inverse modeling techniques, such as Markov Chain Monte Carlo methods. By replacing computationally intensive iterative processes with a direct, learned mapping, GenAI4UQ enables efficient calibration of input parameters and generation of predictions directly from observations. The software supports rapid ensemble forecasting with robust uncertainty quantification while maintaining computational and storage efficiency, as well as a versatile hyperparameter auto-tuning framework.

Target audience

Science teams interested in uncertainty quantification and inverse modeling.

License: MIT

Additional resources

  •  Repository
  •  Documentation (methodology paper)

 

4) libROM

A reduced-order modeling library for a wide range of data-driven physical simulation methods

Description

libROM is a lightweight, scalable C++ library for data-driven physical simulation methods from the intrusive projection-based reduced order models to non-intrusive black-box approaches. It is the main tool box that the reduced order modeling team at Lawrence Livermore National Laboratory uses to develop efficient model order reduction techniques and physics-constrained data-driven methods.

Target audience

Science teams interested in data-driven reduced order methods

License: Apache-2.0 OR MIT

Package links

  • Spack: librom

Additional resources

  •  Website
  •  Repository (main library)
  •  Repository (Python interface)
  •  Documentation

     

5) TAGTorch

A comprehensive suite of tools for analyzing and leveraging symmetry, equivariance, and topological properties in PyTorch deep learning models

Description

Topology, Algebra, and Geometry Torch (TAGTorch) is an open-source PyTorch library that provides reusable implementations of geometry-, topology-, and symmetry-based methods for machine learning. The library brings together tools for building mathematically informed neural networks as well as analyzing datasets and trained models through a unified, PyTorch-native interface.

Target audience

TAGTorch is designed for both machine learning researchers and domain scientists interested in incorporating mathematically grounded methods into existing PyTorch workflows without requiring expertise in computational topology, differential geometry, or group theory.

License: BSD-2-Clause

Additional resources

  •  Repository
  •  Documentation

PNNL

  • Get in Touch
    • Contact
    • Careers
    • Doing Business
    • Environmental Reports
    • Security & Privacy
    • Vulnerability Disclosure Policy
    • Notice to Applicants
  • Research
    • Scientific Discovery
    • Energy Resiliency
    • National Security
Subscribe to PNNL News
Department of Energy Logo Battelle Logo
Pacific Northwest National Laboratory (PNNL) is managed and operated by Battelle for the Department of Energy
  • YouTube
  • Facebook
  • X (formerly Twitter)
  • Instagram
  • LinkedIn