Researchers developed a new technique that combined mass spectrometry and label-free optical imaging to map molecular and structural changes in healthy and diseased lung tissue, providing new insight into bronchopulmonary dysplasia.

Separating quantum circuit wiring from molecular data allows researchers to more efficiently perform quantum simulations

Across 47 sites in the Yakima River Basin of Washington State, faster oxygen consumption occurred with warmer water, more nutrients, and more suspended solids.

Researchers reveal how uncharacterized molecules affect the diversity and composition of dissolved organic matter in rivers.

Measurements show river flow volumes and seasonal timing have shifted; models project where flows will rise, fall, or shift in the future.

Demonstrated that cathodic potential accelerates aqueous phase benzaldehyde hydrogenation.

Artificial intelligence helps analyze images and reduce uncertainty for a key measure of watershed function.

Dynamic organic matter traits tied to reactions can surpass static descriptors in explaining decomposition rates and responses to environmental change.

Using an AI approach to combine outputs from microbial models and apply them as inputs to reactive-transport models reduces computational time by several orders of magnitude.

Amine functionalized graphene oxide yields laminates with an enhanced capacity to adsorb rare earth elements, improved water transport, and greater stability for effective membrane-based separation of critical minerals.

Establishing how electronic redistribution, protonation, and solvent rearrangement are coupled during a proton-coupled electron transfer process.

Integrating experiments and modeling show how a fungal exudate-inspired substrate mixture elicits an emergent growth phenotype and metabolic responses in Pseudomonas putida.

By selectively stabilizing either a right- or left-handed helical pose of its substrate, an enzyme tunes the final product.

Researchers showed that spiking neural networks can be accurate for regression problems, opening opportunities for efficient neuromorphic computing.

Research provided definitive spectroscopic characterization, reactivity, and deactivation of a reactive monomeric diphosphine-copper hydride intermediate.

Uncovered how the choice of carbon source influences the stress tolerance, redox balance, and regulatory responses of yeast, which can help provide resilience against scale-up challenges.

Five PNNL innovations earned 2026 R&D 100 Awards for advances in biotechnology, manufacturing, critical minerals, and nuclear security.

New software enables the study of nuclear quantum effects in large, condensed phase systems up to 10× faster than traditional methods.

Protein and water environments set the overall redox scale of iron-sulfur clusters, but local coordination geometry fine-tunes the final potential.

New theoretical framings of quantum dynamics enable better quantum-based simulation of molecular systems and dynamics.