Scientists map how transitions from day to night control gene regulatory networks in cyanobacteria, revealing key orchestrators of metabolic switching.

Scientists uncover how cyanobacteria's circadian cycle controls carbon and energy metabolism, increasing carbon dioxide-to-bioproducts yields.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

Computing and artificial intelligence aid scientists who seek to understand function-driven design and control of biological systems.

New apps help researchers with statistical analyses of data.

The new PTM-Psi workflow opens the door for uncovering molecular insights within proteomics datasets.

A team of researchers from PNNL provided technical knowledge and support to test a suite of techniques that detect genetically modified bacteria, viruses, and cells.

Scientists developed a process (or pipeline) that combined molecular probes—a specific chemical that binds to microbes carrying out a particular function—with a method that isolated these cells from their complex community.

Scientists screen for nanobodies that recognize wild type and mutant functional proteins to develop a framework to disrupt protein interactions that can cause disease.

The diversity and function of organic matter in rivers at a large scale are influenced by factors, such as the types of vegetation covering the land, the energy characteristics, and the breakdown potential of the molecules.

PNNL researchers combined deep operator networks with spectral methods to efficiently and accurately solve complex equations.

ICON science is a Department of Energy-developed framework to enhance scientific outcomes via more intentional design of research efforts across all domains of science.

A new microbial community model reveals previous exposure to hydrologic variation influences a species’ specialized biogeochemical functions.

Detailed characterization of molecules in, under, and along the Columbia River reveal potential mechanisms for biogeochemical cycling.

Integrating hydrogeology and biogeochemistry are required to model the dynamics of geochemical processes occurring in river corridor zones where groundwater and surface water mix.

Theoretical analysis reveals flow variations that happen over longer time periods affect a plume’s spread and center of mass.

Principles derived from coastal wetlands to describe wetland channel cross-sections were applicable to the Columbia River estuary, but not the tidal river.

An updated version of a widely used database will provide powerful insights into the global carbon cycle.