Integrating new functions into a genome-scale model enabled researchers to simulate and experimentally validate viral hijacking pathways.

Structural proteomics reveal how cyanobacteria adapt to changing light.

Researchers use multiomics to confirm role of lipid synthesis during infection, leading to model of how to restrict virus replication.

In a recent study, PNNL researchers found that noncrystalline mineral surfaces can bind microbial residues to build soil organic matter.

Capturing protein structural changes in host cells exposes vulnerabilities exploited by viruses to hijack cellular machinery.

Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.

A new study led by PNNL researcher TC Chakraborty provides some answers about how irrigated agricultural land near cities affects urban heat stress.

CACTUS provides AI-powered cheminformatics for autonomous science.

This project sought to assure that research activities centered around different sampling and monitoring efforts in northwest Ohio would not disturb any historical cultural resources.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

University of Washington Professor David Baker won the 2024 Nobel Prize in Chemistry for computational protein design.

Despite the widespread presence of RNA viruses in soils, little is known about the relative contributions and interactions of biological and environmental factors shaping the composition of soil RNA viral communities.

Early life exposure to polycyclic aromatic hydrocarbons (PAHs), found in smoke, has been linked to developmental problems. To study the impacts of these pollutants, PAH metabolism in infants and adults were compared.

PMedIC, the PNNL and OHSU joint research collaboration, contributes to student success and impact in biomedicine.

A compilation of soil viral genomes provides a comprehensive description of the soil virosphere, its potential to impact global biogeochemistry, and an open database for future investigations of soil viral ecology.

A multi-institutional team of researchers conducted a 13C-labeling greenhouse study using a semi-arid grassland soil, where they tracked the fate of 13C-labeled inputs from living roots and decaying roots from annual grass Avena barbata.

Discovering and measuring the spatial organization of proteins within cells allows scientists to map complex proteoforms across tissues with near-cellular resolution.

Data reveals mechanisms in our bodies that can help us fight viral pathogenesis.

New apps help researchers with statistical analyses of data.