Small teams in the Biological Sciences Division at PNNL and at EMSL—the Environmental and Molecular Sciences Laboratory, an Office of Science user facility at PNNL—are pros at preparation.
New research from PNNL and Washington State University collaborators connects the microbiome in the gut to circadian rhythms, suggesting a role for the microbiome as an internal regulator.
The ChemSpace Tool, when fully developed, is intended to divide chemical space into three subsets: the detectable space, the identifiable space, and the region that includes compounds that are not detectable or identifiable.
SAGE is a high-efficiency genome integration strategy for bacteria that makes the stable introduction of new traits simple for newly discovered microbes.
Variations in burn severity are a key control on the chemical constituents of dissolved organic matter delivered to streams within a single burn perimeter.
A multi-omics analysis provides the framework for gaining insights into the structure and function of microbial communities across multiple habitats on a planetary scale
Gosline works to develop computational algorithms that are uniquely targeted for rare disease work by doing foundational research in model system development. This work can be expanded to all model systems in human disease.
Data-driven autonomous technology to rapidly design and deliver antiviral interventions targeting SARS-CoV-2 to reduce drug discovery timeline and advance bio preparedness capabilities.
The Joint Appointment program at PNNL is one of the most diverse among other U.S. national laboratories, involving nearly 60 universities and research institutions in the United States and abroad.
A new web-based tool provides easy-to-understand progress metrics and other data about groundwater cleanup sites overseen by the DOE Office of Environmental Management.
PNNL scientists have proposed an "adaptive site management" cleanup strategy for the Hanford Site's Central Plateau that incorporates a structured, flexible approach to environmental remediation.
Ocean biogeochemical modeling software now available as open source to help researchers predict impacts of pollution, sea level rise, and climate change.
Integrating hydrogeology and biogeochemistry are required to model the dynamics of geochemical processes occurring in river corridor zones where groundwater and surface water mix.