Biological
Sciences
and Omics

Biological Sciences and Omics

Biological Sciences and Omics market icon

As a leader in the field of integrated omics, PNNL has developed innovative methods and identified critical biomarkers for advancing the detection, diagnosis, and treatment of diseases, such as diabetes, cancer, lymphoma, viruses, and liver fibrosis. These methods enable the development of personalized medicine techniques that can diagnose and treat some of the world’s most challenging diseases. For example, a PNNL-developed antibody is being used to predict and monitor drug responsiveness for asthmatics. We invite you to explore the possibilities of licensing our innovations from the Biological Science & Omics portfolio to make an impact on human and animal health.

 

Available Technologies Spotlight

PERK Inhibitor for Treatment of MERS-Coronavirus

Human coronaviruses are emerging pathogens that can cause significant, global morbidity and mortality. The Middle East respiratory syndrome...
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In the ongoing mission to curb the impact of coronaviruses, PNNL’s PERK Inhibitor Coronavirus Treatment may help reduce mortality in infected patients.

Biomarkers for Liver Fibrosis

Liver fibrosis may result from a wide variety of conditions including chronic alcohol exposure, hepatitis B virus (HBV) infection, non-alcoholic fatty...
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Blood samples from 60 HCV infected patients categorized into low fibrosis stages 0 & 1 and high fibrosis stages 4, 5 and 6, were used to identify differentially abundant panels of blood protein markers. Each column represents one of the 60 patients and each row one of the 78 significant proteins. Decrease in relative abundance is shown by green and increase by red.

Peptoid Nanomembranes

Biological cell membranes protect cells from toxins and encourage nutrients to enter. They also repair themselves. Manufactured membranes with similar...
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PNNL’s synthetic, protein-like polymers (or peptoids) self-assemble into membrane-mimetic, two-dimensional nanomaterials that mimic natural cell-membrane-like functions.

Probes for Function-Based Microbial Sorting

More and more, scientific advancements in energy production, plant nutrition, and bioremediation rely on characterizing microbial communities beyond...
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PNNL's microbial probe is the only technology of its kind that can determine the function of microbes, enzymes, and the like in biological samples, such as air, soil, water, and host-associated, shown here in the human gut.

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