Genesis Mission

Genesis Mission

(Department of Energy)

Pacific Northwest National Laboratory (PNNL) is a key partner in the Genesis Mission, the Department of Energy’s (DOE’s) integrated ecosystem to accelerate discovery and strengthen U.S. leadership in artificial intelligence (AI)-powered science. Drawing on its deep expertise in the design and application of AI, novel computing paradigms, and fundamental science, PNNL is creating AI solutions to aid autonomous discovery science in chemistry, materials, and biology, speed environmental permitting, and ensure reliable, secure energy grids. Together, these efforts and more make PNNL a transformational AI engine advancing the nation's scientific, energy, and national security missions.

Pillars of the Genesis Mission

graphical illustration of the circular relationship between the 5 pillars of the genesis project

The Genesis Mission is arranged in five pillars that integrate DOE’s and the National Nuclear Security Administration’s:

  • Frontier-class AI models and autonomous agents (Models pillar)
  • Unique data assets across science, energy, and security (Data pillar)
  • World-class high-performance computing, user and production facilities (Infrastructure pillar)
  • Lighthouse Problems pillar
  • Innovative public–private Partnerships pillar

PNNL plays a key role as the co-lead of the Models pillar. 


an illustrated icon showing scientific symbols inside the silhouette of a person's head

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