Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

Researchers developed a robust, cost-effective, and easy-to-use cap-based technique for spatial proteome mapping, addressing the lack of accessible proteomics technologies for studying tissue heterogeneity and microenvironments.

CACTUS provides AI-powered cheminformatics for autonomous science.

Federal environmental permitting process to be fast-tracked with AI-powered tools and cloud-supported data analysis.

Ljiljana Paša-Tolić, a PNNL fellow, is the recipient of the 2024 International Mass Spectrometry Foundation’s Jochen Franzen Award. 

PNNL contributes to a nationwide research consortium investigating the molecular mechanisms triggered by endurance training.

PNNL scientists took thousands of measurements of firefighters in training to learn more about how the body responds to vigorous exercise.

Summer internship programs with partnering colleges provide pathways for students to explore careers in science, technology, engineering, and math.

This study profiled the 24-hour rhythmicity in bile salt hydrolase enzyme activity using simple fluorescence assay and the results showed that this rhythmicity is influenced by feeding patterns of the host.

Joshua Adkins and Jamie Lo will lead PMedIC, Pacific Northwest National Laboratory and Oregon Health & Science University’s joint research institute.

New research from PNNL and Washington State University collaborators connects the microbiome in the gut to circadian rhythms, suggesting a role for the microbiome as an internal regulator.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.

PNNL Biomedical Scientist Geremy Clair has taken on new roles as an editor for two journals; Frontiers In Cellular And Infection Microbiology and Frontiers In Molecular Biosciences.

James Ang, John Feo, and Marco Minutoli organized a high performance computing workshop at the prestigious ISC High Performance 2022 conference.

Study highlights microbiome’s role in regulating xenobiotic metabolism.

The nested nanoPOTS chip is the next generation of technology developed at PNNL to prepare single cells for proteomics.

Customized molecular tools identify specific microbial functions that are key to healthy people and environments.

High school students from across Washington State competed in the Pacific Northwest Regional Science Bowl, hosted online by PNNL, for a chance to advance to the national competition in May.

Red teaming for CPS, the process of challenging systems, involves a group of cybersecurity experts to emulate end-to-end cyberattacks following a set of realistic tactics, techniques, and procedures.