Predicting how organisms’ characteristics respond to not only their genes, but also their environments (a nascent field called predictive phenomics) is extraordinarily challenging. Researchers at PNNL are using AI to tackle that challenge.

As Laboratory Director Steve Ashby pens his last monthly column, he highlights PNNL’s accomplishments with pride and gratitude.

PNNL researchers have found yet another way to turn trash into treasure: using algal biochar, a waste production from hydrothermal liquefaction, as a supplementary material for cement.

Researchers are uncovering the secrets of a fast-acting molecular messaging network that helps determine how the genetic code plays out.

From producing radioisotope generators to recovering source materials, researchers are meeting a growing need for medical radioisotopes.

The first direct molecular-scale evidence of the temperature-driven transformation of the coordination environment of ytterbium at geologically relevant conditions.

Understanding molecular modifications of proteins in the red yeast could help scientists re-engineer the organism’s phenotype.

PNNL researchers continue to deliver high-quality, high-impact research on radioactive waste and nuclear materials management, earning “Papers of Note” and “Superior Paper” awards.

Alex Beliaev, a biologist at PNNL, was named a Society for Industrial Microbiology and Biotechnology fellow.

Dušan Veličković, a PNNL mass spectrometry imaging scientist received a $2.1 million grant to develop techniques to understand how changes in carbohydrate structure affect human health.

Researchers from PNNL and Parallel Works, Inc., applied machine learning methods to predict how much oxygen and nutrients are used by microorganisms in river sediments.

PNNL researchers showcased subsurface sampling and remediation expertise at the 2025 Federal Remediation Technologies Roundtable.

This study used historical data, remote sensing, and aquatic sensors to measure how far wildfire impacts propagated through the watershed after the 2022 Hermit’s Peak/Calf Canyon fire, New Mexico’s largest wildfire in history.

The Coastal Observations, Mechanisms, and Predictions Across Systems and Scales: Field, Measurements, and Experiments project established a network of observational field sites across Chesapeake Bay and western Lake Erie.

PNNL has created and licensed a system that sniffs out trace levels of fentanyl, other drugs and explosives through the air.

Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.

Flexible, high-throughput proteomics approach identifies protein modifications related to pancreatic stress and insulin production.

Directionally biased electrostatic interactions are the key to significantly tuning the reduction potential of iron/sulfur clusters.

A new study led by PNNL researcher TC Chakraborty provides some answers about how irrigated agricultural land near cities affects urban heat stress.

Jeff Burghardt is the chair of the technical program for the 59th US Rock Mechanics/Geomechanics Symposium of the American Rock Mechanics Association.