A multi-omics analysis provides the framework for gaining insights into the structure and function of microbial communities across multiple habitats on a planetary scale

A rich and largely untapped reservoir of lipids in soil environments was used to examine microorganisms’ physiological responses to drying-rewetting cycles.

Snekmer is an application for building and searching protein family models and novel sequence clusters.

Gosline works to develop computational algorithms that are uniquely targeted for rare disease work by doing foundational research in model system development. This work can be expanded to all model systems in human disease.

Data-driven autonomous technology to rapidly design and deliver antiviral interventions targeting SARS-CoV-2 to reduce drug discovery timeline and advance bio preparedness capabilities.

A team from the Environmental Molecular Sciences Laboratory published research, demonstrating that the soil microbes were directly involved in the stabilization of soil organic carbon and mineral weathering.

A paper by PNNL researchers has been chosen as one of 32 NIEHS Papers of the Year—a top 1% honor in the research field.

Microbes that were previously frozen in soils are becoming more active. This study demonstrates the diverse RNA viral communities found in thawed permafrost.

Findings show method to better prepare human lung tissue for study; it represents the latest mass spectrometry-based omics advances.

New research findings published in Science Advances (November 2022), help explain the progression of Alzheimer-related dementia in each patient. The findings outline a biological classification system that predicts disease severity.

Studying how microorganisms behave in space could facilitate farming in the final frontier and lead to better crops on Earth.

Silicone wristbands could be more convenient option for collecting exposure data.

Organismal contribution and community interaction drive soil organic matter breakdown by microbes.

Identifying a novel gene function on soil viruses.

Microbes and viruses play key roles in carbon and nitrogen cycling in riverbed sediments.

Proteins from “auxiliary” genes in soil viruses play a role in the carbon cycle and climate, scientists have found.

We are pleased to welcome 20 new joint appointees to PNNL.

Read interviews with the new Laboratory fellows to learn about their contributions to their field, what drives them, and how their research is making the nation safer, greener, and more resilient.

Forms of nitrogen released by nitrogen-fixing bacteria differ across sampling scales and in structured environments.

Dominant and functionally important soil microbes show strong, predictable, and distinctly different associations with continental-scale gradients in climate, vegetation, and soil moisture.