The ChemSpace Tool, when fully developed, is intended to divide chemical space into three subsets: the detectable space, the identifiable space, and the region that includes compounds that are not detectable or identifiable.

Methods review suggests ways to use artificial intelligence and machine learning to handle missing data when integrating two or more omics approaches.

COVID-19 infections at PNNL early in the pandemic were caused by a wide variety of viral sequences, according to a new analysis by Laboratory researchers.

The Northwest Connected Communities Summit brought together representatives of five Department of Energy-funded Connected Communities Projects to share ideas and discuss potential collaboration opportunities.

SAGE is a high-efficiency genome integration strategy for bacteria that makes the stable introduction of new traits simple for newly discovered microbes.

Department of Energy Office of Electricity Assistant Secretary Gene Rodrigues makes his first visit to PNNL.

Variations in burn severity are a key control on the chemical constituents of dissolved organic matter delivered to streams within a single burn perimeter.

First-of-its-kind genomic catalog lends insight into previously unknown processes at the river’s edge.

A PNNL innovation uses steam to recover heat from the high-temperature reactor effluent in the HTL process, substantially reducing the propensity for fouling and potentially reducing costs.

PNNL welcomes new joint appointments to expand the research productivity and scientific impact of both PNNL and the university partners, broadening the base of expertise at each institution and helping to build interdisciplinary teams.

Department of Energy, Office of Science Director Asmeret Asefaw Berhe visited PNNL to learn about the Lab’s drive to conduct discovery science, commitment to science for an equitable future, and development of a diversified STEM workforce.

A multi-omics analysis provides the framework for gaining insights into the structure and function of microbial communities across multiple habitats on a planetary scale

A rich and largely untapped reservoir of lipids in soil environments was used to examine microorganisms’ physiological responses to drying-rewetting cycles.

Snekmer is an application for building and searching protein family models and novel sequence clusters.

PNNL researchers discovered a faster, more economical method to verify the amount of biofuel in mixtures of bio and fossil fuel.

Gosline works to develop computational algorithms that are uniquely targeted for rare disease work by doing foundational research in model system development. This work can be expanded to all model systems in human disease.

Data-driven autonomous technology to rapidly design and deliver antiviral interventions targeting SARS-CoV-2 to reduce drug discovery timeline and advance bio preparedness capabilities.

Report for the Oregon Public Utility Commission highlights innovations and best practices for resilience and utility planning could be helpful to other states as well.

A team from the Environmental Molecular Sciences Laboratory published research, demonstrating that the soil microbes were directly involved in the stabilization of soil organic carbon and mineral weathering.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.