Integrating experiments and modeling show how a fungal exudate-inspired substrate mixture elicits an emergent growth phenotype and metabolic responses in Pseudomonas putida.

By selectively stabilizing either a right- or left-handed helical pose of its substrate, an enzyme tunes the final product.

Uncovered how the choice of carbon source influences the stress tolerance, redox balance, and regulatory responses of yeast, which can help provide resilience against scale-up challenges.

PNNL researchers are bringing a data-driven approach to unleashing the potential of geothermal energy.

Five PNNL innovations earned 2026 R&D 100 Awards for advances in biotechnology, manufacturing, critical minerals, and nuclear security.

A new PNNL game teaches players about obstacles that fish face during migration.

New partnership agreement to focus on AI, robotics, and advanced energy systems.

Study shows the advantages of top-town proteomics for characterizing histones.

At the summit, PNNL engaged with partners and investors, highlighting seven projects that accelerate the deployment of new energy technologies.

Integrating new functions into a genome-scale model enabled researchers to simulate and experimentally validate viral hijacking pathways.

Stakeholders convened at PNNL to build a shared understanding of energy storage siting, permitting, safety, and local engagement.

PNNL has developed a next-generation electrical resistivity tomography system for DOE that uses E4D software and AI-enhanced modeling to produce real-time subsurface images that help guide environmental remediation decisions.

Replacing commercial acid with acidic waste enables researchers to improve nickel extraction efficiency, lower projected costs, and improve process economics.

A microbial community expresses a phenotype of interest ~20 percent higher than the sum of each member species.

Connecting energy generation, electricity storage, and using sensors and control software to track load, including precommercial market marine energy generation technologies.

Structural proteomics reveal how cyanobacteria adapt to changing light.

Secretary Wright visited PNNL's campus in Richland, Washington, late last year to meet with innovators in chemistry, biology, computing, and more.

Researchers use multiomics to confirm role of lipid synthesis during infection, leading to model of how to restrict virus replication.

PNNL researchers Daniel Deng and Yehia Ibrahim join the 2025 class of National Academy of Inventors Fellows.

In a recent study, PNNL researchers found that noncrystalline mineral surfaces can bind microbial residues to build soil organic matter.