A microbial community expresses a phenotype of interest ~20 percent higher than the sum of each member species.

Structural proteomics reveal how cyanobacteria adapt to changing light.

Secretary Wright visited PNNL's campus in Richland, Washington, late last year to meet with innovators in chemistry, biology, computing, and more.

Researchers use multiomics to confirm role of lipid synthesis during infection, leading to model of how to restrict virus replication.

PNNL researchers Daniel Deng and Yehia Ibrahim join the 2025 class of National Academy of Inventors Fellows.

Capturing protein structural changes in host cells exposes vulnerabilities exploited by viruses to hijack cellular machinery.

PNNL researchers developed a new computational workflow to study day-to-night gene expression dynamics of cyanobacterium in real time.

Understanding molecular modifications of proteins in the red yeast could help scientists re-engineer the organism’s phenotype.

Engineers at PNNL devised a system that allows radar antennae to maintain stable orientation while mounted on platforms in open water that pitch and roll unpredictably. They were recently invited to participate in DOE's I-Corps program.

Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.

Flexible, high-throughput proteomics approach identifies protein modifications related to pancreatic stress and insulin production.

Scientists uncover how cyanobacteria's circadian cycle controls carbon and energy metabolism, increasing carbon dioxide-to-bioproducts yields.

Scientists map how transitions from day to night control gene regulatory networks in cyanobacteria, revealing key orchestrators of metabolic switching.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

Computing and artificial intelligence aid scientists who seek to understand function-driven design and control of biological systems.

The nation is closer to its offshore wind energy goals than ever before, but better wind forecasting is still needed. To address this challenge, PNNL and collaborators are charting a new course with help from novel technology.

The new PTM-Psi workflow opens the door for uncovering molecular insights within proteomics datasets.

Scientists developed a process (or pipeline) that combined molecular probes—a specific chemical that binds to microbes carrying out a particular function—with a method that isolated these cells from their complex community.