Fish passage refers to the ability to effectively and efficiently allow fish to move through a water system, including successfully navigating human-made structures like dams and culverts, which can impede their journey.

Bioinformatics uses computers to make sense of the vast amount of data researchers can now glean from living things. These things can be as seemingly simple as a single cell or as complex as the human immune response. Bioinformatics is a tool that helps researchers decipher the human genome, look at the global picture of a biological system, develop new biotechnologies, or perfect new legal and forensic techniques, and it will be used to create the personalized medicine of the future.

Advanced computing testbeds, the proving grounds for new machines, are central to the development of next-generation computers. They allow researchers to explore a complex and non-linear design space and facilitate the evaluation of new computing technologies in terms of performance and efficiency on critical scientific workloads. These “laboratories of machines,” in which multiple components are available for experimentation, are critical to the next greatest advancements in computation.