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Biological
Sciences
Division

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The Biological Sciences Division has 16 collaborative, interdisciplinary teams working to understand how plants, microbes, and algae function in a way that helps predict their response to environmental change and their potential for energy production. Insights into the workings of human tissues reveal how toxins and pathogens could influence human health. Our research inspires biology-based advances to tackle some of the biggest challenges our world faces in ecosystem sustainability and human health. Learn more about how PNNL teams explore these areas using instrumentation that provides large-scale, molecular-level information and computational tools to efficiently process vast amounts of data.

Biological Systems Science
Computational Biology
Integrative Omics

 

Featured News & Highlights

Graphic representation of microbes in a soil environment.
DECEMBER 4, 2025
Research Highlight

Microbial Residues Last Longer in Soil When Bound to Noncrystalline Minerals

In a recent study, PNNL researchers found that noncrystalline mineral surfaces can bind microbial residues to build soil organic matter.
( Read More )
Illustration of a cold virus particle on the left attacking a cell on the right.
NOVEMBER 17, 2025
News Release

Scientists Identify Two Key Targets of Common Cold Virus

PNNL researchers are opening up a new front in the fight to stop viral pathogens, protecting people against multiple viruses.
( Read More )
A graphic of cartoon people and the Earth.
NOVEMBER 17, 2025
Article

Beyond “Science as Usual”

Distributed science is thriving at PNNL, where scientists share data and collaborate with researchers around the world to increase the impact of the work.
( Read More )
Jeff Czajka in his laboratory space at PNNL.
SEPTEMBER 23, 2025
Feature

At PNNL, AI Is Accelerating the U.S. Bioeconomy

Predicting how organisms’ characteristics respond to not only their genes, but also their environments (a nascent field called predictive phenomics), is extraordinarily challenging. Researchers at PNNL are using AI to tackle that challenge.
( Read More )
Photograph shows Tong Zhang on the left, looking into the camera, with laboratory equipment behind him and to the right.
SEPTEMBER 3, 2025
News Release

Scientists Probe Powerful Molecular Messaging System That Goes Beyond DNA

Researchers are uncovering the secrets of a fast-acting molecular messaging network that helps determine how the genetic code plays out.
( Read More )
rendering of a microscopic bacteriophage
MARCH 26, 2025
Feature

Advancing Human Health by Exploring Viral Dark Matter

Over the next four years, PNNL and University of Arizona will develop open-source computational tools to better identify and characterize the viruses associated with the human microbiome.
( Read More )
Composite image of Sara Gosline (left) and Jason McDermott (right)
MARCH 25, 2025
Feature

Unseen Forces: How Scientists Map the Invisible Interactions of Life

Armed with some of the world’s most advanced instrumentation, researchers at PNNL are working to analyze huge amounts of data and uncover hidden biological connections.
( Read More )
Illustration shows blue hydrangeas on the left and pink hydrangeas on the right,. The colors are the result of the pH of the soil.
FEBRUARY 13, 2025
News Release

Beyond DNA: How Environments Influence Biology to Make Things Happen

This week at AAAS, PNNL scientists discuss phenomics and the factors that influence DNA instructions to bring about the world around us.
( Read More )
An image of someone doing lab work.
DECEMBER 9, 2024
Article

NASA Funds Pacific Northwest Consortium to Advance Life Sciences Research in Space

NASA has awarded $2.5 million to the BioS-ENDURES consortium, led by the University of Washington and including WSU and PNNL, to advance space life sciences research supporting human health in space and Earth-based applications.
( Read More )
Kenton Rod and Regan McDearis hold custom stakes for soil research
OCTOBER 31, 2024
Article

High Stakes in Soil Microbiology

PNNL's McDearis and Rod designed a new device—a porous soil stake—that, once installed, enables repeated sampling of a specific soil site at multiple depths, without further disrupting the soil.
( Read More )

The Biological Sciences Division has 16 collaborative, interdisciplinary teams that inspire biology-based advances to tackle some of the biggest challenges our world faces in ecosystem sustainability, bioenergy, human health and national security. 

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