Projects and Programs


Phenotypic Response of the Soil Microbiome to Environmental Perturbations

Advancing our understanding of how soil microbial communities respond to—and affect—changing environmental conditions


person wearing a life jacket and rubber boots walking along a rocky riverbank carrying a cooler

River Corridor Hydrobiogeochemistry Science Focus Area

Transforming our understanding of spatial and temporal dynamics in river corridor hydrobiogeochemical functions, from molecular reaction to watershed and basin scales


Riverbed with WHONDRS spelled out in the sand

Worldwide Hydrobiogeochemical Observation Network for Dynamic River Systems (WHONDRS)

A research consortium tracing coupled hydrologic, biogeochemical, and microbial processes within river corridors


Cellular metabolites

Pacific Northwest Advanced Compound Identification Core (PNACIC)

Tackling one of the greatest challenges in bioanalysis―comprehensive, unambiguous identification of metabolites



Pacific northwest bioMedical Innovation Co-laboratory (PMedIC)

A joint collaboration of PNNL and Oregon Health & Science University to integrate patient-specific data with imaging and clinical results to customize disease treatment and improve health


harbor with trees lining waterway

Superfund Research Program

A joint collaboration of PNNL and Oregon State University studying the health effects of polycyclic aromatic hydrocarbons


illustration of woman lifting weights with network overlaid on her body representing molecules in her cells

Molecular Transducers of Physical Activity Consortium (MoTrPAC)

A national research consortium to identify molecular signatures of the health benefits of exercise 



m/q Initiative

Transforming the utility of mass spectrometry through a comprehensive, unified, and predictive understanding of the chemistry and physics of all ions throughout an experiment, which is then used to predict a quantitative spectral response


Predictive Phenomics

Predictive Phenomics Initiative

The team will use a reverse genomics approach to target the molecular basis of function