Research Areas

At PNNL, our biology researchers explore the molecular details of microbiomes, environmental systems, and human health to understand their function and how they respond to change. Then, we make predictions and even manipulate the systems to take steps toward the greater good. Put simply, our goal is to design biological solutions that make the world a better place. 
research bio page

Chemical Biology
Computational Biology
Ecosystem Science
Human Health
Integrative Omics 
Microbiome Science 

2022 Journal Covers

Analytical Chem_Journalcover2022

 

 

 

 

 

 

 

Hollerbach AL, RV Norheim, P Kwantwi-Barima, RD Smith, and YM Ibrahim. “A Miniature Multilevel Structures for Lossless Ion Manipulations Ion Mobility Spectrometer with Wide Mobility Range Separation Capabilities.” Analytical Chemistry 2022 94 (4), 2180-2188 DOI: 10.1021/acs.analchem.1c04700

2021 Journal Covers

2021 Journal Covers - BSD

 

 

 

 

 

Joshi RP, A McNaughton, DG Thomas, CS Henry, SR Canon, LA McCue, and N Kumar. “Quantum Mechanical Methods Predict Accurate Thermodynamics of Biochemical Reactions.” ACS Omega 2021 6 (14), 9948-9959 DOI: 10.1021/acsomega.1c00997

Stoddard EG, S Nag, J Martin, KJ Tyrrell, T Gibbins, KA Anderson, AK Shukla, R Corley,  AT Wright , JN Smith. “Exposure to an Environmental Mixture of Polycyclic Aromatic Hydrocarbons Induces Hepatic Cytochrome P450 Enzymes in Mice.” Chem Res Toxicol. 2021 Sep 20;34(9):2145-2156. doi: 10.1021/acs.chemrestox.1c00235.

McNaughton AD, EL Bredeweg, J Manzer, J Zucker, N Munoz Munoz, MC Burnet, ES Nakayasu, KR Pomraning, ED Merkley, Z Dai, WB Chrisler, SE Baker, PC St. John, and N Kumar. “Bayesian Inference for Integrating Yarrowia lipolytica Multiomics Datasets with Metabolic.” ACS Synthetic Biology 2021 10 (11), 2968-2981 DOI: 10.1021/acssynbio.1c00267

Joshi RP, NWA Gebauer, M Bontha, M Khazaieli, RM James, JB Brown, N Kumar. “3D-Scaffold: A Deep Learning Framework to Generate 3D Coordinates of Drug-like Molecules with Desired Scaffolds.” J Phys Chem B. 2021 Nov 11;125(44):12166-12176. doi: 10.1021/acs.jpcb.1c06437. Epub 2021 Oct 18. PMID: 34662142.