We present UNiquant, a new software program for analyzing stable isotope labeling (SIL) based quantitative proteomics data. UNiquant surpassed the performance of two other platforms, MaxQuant and Mascot Distiller, using complex proteome mixtures having either known or unknown heavy/light ratios. UNiquant is compatible with a broad spectrum of search engines and SIL methods, providing outstanding peptide pair identification and accurate measurement of the relative peptide/protein abundance.
Published: March 4, 2011
Citation
Huang X., A.V. Tolmachev, Y. Shen, M. Liu, L. Huang, Z. Zhang, and G.A. Anderson, et al. 2011.UNiquant, a Program for Quantitative Proteomics Analysis Using Stable Isotope Labeling.Journal of Proteome Research 10, no. 3:1228-1237.PNNL-SA-74145.doi:10.1021/pr1010058