NMR evidence is presented indicating that the exceptional conformational dynamics found at TpA steps in DNA is general to all immeidate sequence contexts. One easily tractable NMR parameter that is sensitive to Tpa base dynamics is the resonance linewidth of the TpA adenine HW proton.
Revised: July 5, 2001 |
Published: June 1, 2000
Citation
Mcateer K., and M.A. Kennedy. 2000.NMR Evidence for Base Dynamics at all TpA Steps in DNA.Journal of Biomolecular Structure and Dynamics 17, no. 6 (2000):1001-1009.PNNL-SA-33101.