July 30, 2001
Journal Article

A new technique for unbiased external ion accumulation in a quadrupole two-dimensional ion trap for electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry

Abstract

External ion accumulation in a 2D multipole trap has been shown to increase the sensitivity, dynamic range and duty cycle of an FTICR mass spectrometer. However, it is important that trapped ions be detected without significant bias at longer accumulation times in the external 2D multipole trap. With increasing ion accumulation time pronounced m/z discrimination was observed when trapping ions in an accumulation quadrupole. In this work we show that superimposing lower rf-amplitude dipolar excitation over the main rf-field in the accumulation quadrupole results in disruption of the m/z discrimination and can potentially be used for achieving unbiased external ion accumulation with FTICR.

Revised: December 10, 2001 | Published: July 30, 2001

Citation

Belov M.E., E.N. Nikolaev, K. Alving, and R.D. Smith. 2001. A new technique for unbiased external ion accumulation in a quadrupole two-dimensional ion trap for electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. Rapid Communications in Mass Spectrometry 15, no. 14:1172-1180. PNWD-SA-5483.