This report highlights the work that has been completed on concentration calculations, uncertainties and minimum detectable concentration (MDC) for radioxenon collection systems. A discussion on the theory behind MDC calculations is given. In addition, regions of interest (ROI) and their role in correcting for both memory effects and interference terms are given in detail. A detailed derivation and walkthrough of the calculation is given with some discussion at each stage of the equation. Finally, some specific examples are given with typical numbers from an ARSA system as a guide.