After completion of the sequencing phase of the genome projects, attention has turned to determine the structure and function of all the proteins encoded by the newly sequenced genes. Structural proteomics projects are expected to answer basic questions about the conformational space available to proteins, and reveal information about pharmaceutical applications. The number of pharmaceutical targets is expected to increase dramatically in the post-genomic era, and detailed information about the structure of the proteins will facilitate the development of drugs against these potential targets (Brower, 2001).
Revised: June 28, 2004 |
Published: March 1, 2002
Citation
Pineda-Lucena A., G. Yi, X. Chang, J.R. Cort, M.A. Kennedy, A.M. Edwards, and C.H. Arrowsmith. 2002.Letter to the Editor: Solution Structure of the Hypothetical Protein MTH0637 from Methanobacterium Thermoautotrophicum.Journal of Biomolecular NMR 22, no. 3:291-294. PNWD-SA-5705.