Human Replication Protein A: Global Fold of the N-terminal RPA-70 Domain Reveals a Basic Cleft and Flexible C-terminal Linker

March 30, 1999

Journal Article

Human Replication Protein A: Global Fold of the N-terminal RPA-70 Domain Reveals a Basic Cleft and Flexible C-terminal Linker

Abstract

Human Replication Protein A (hsRPA) is required for multiple cellular proceeses in DNA metabolism including DNA repair, replication and recombination. It binds single-stranded DNA with high affinity and interacts specifically with multiple proteins.

Revised: September 20, 2001 | Published: March 30, 1999

Citation

Jacobs D.M., A.S. Lipton, N.G. Isern, G.W. Daughdrill, D.F. Lowry, X. Gomes, and M.S. Wold. 1999. Human Replication Protein A: Global Fold of the N-terminal RPA-70 Domain Reveals a Basic Cleft and Flexible C-terminal Linker. Journal of Biomolecular NMR 14, no. 1999:321-331. PNNL-SA-29827.