The silicified L3-poly(N-sopropylacrylamide)/hydroxyapatite nanocomposites by the integration of thermosensitive polymer and heterogenious continuity in 3-D interconnected porous structure have been prepared for the highly controlled drug release without the burst release at the initial time during step-wised temperature changes, and demonstrated the in-vitro cytotoxicity test for biocompatibility.
Revised: May 18, 2007 |
Published: January 15, 2007
Citation
Chang J.H., M.E. Park, Y. Shin, G.J. Exarhos, K.J. Kim, S. Lee, and K. Oh. 2007.Functional Scaffolds of Bicontinuous, Thermoresponsive L3-phase Silica/Hydroxyapatite Nanocomposites.Journal of Materials Chemistry 17, no. 3:238-242.PNNL-SA-53767.doi:10.1039/b609409k