A new heterogeneity analysis approach to discern radiation-induced lung damage was tested on CT images of irradiated rats. The method, combining octree decomposition with variogram analysis, demonstrated a significant correlation with radiation exposure levels, whereas conventional measurements and pulmonary function tests did not. The results suggest the new approach may be highly sensitive for assessing even subtle radiation-induced changes
Revised: September 18, 2013 |
Published: October 1, 2013
Citation
Jacob R.E., M.K. Murphy, J.A. Creim, and J.P. Carson. 2013.Detecting Radiation-Induced Injury Using Rapid 3D Variogram Analysis of CT Images of Rat Lungs.Academic Radiology 20, no. 10:1264-1271.PNNL-SA-93209.doi:10.1016/j.acra.2013.07.001