We present a new software tool for tandem MS analyses that: • accurately calculates the monoisotopic mass and charge of high–resolution parent ions • accurately operates regardless of the mass selected for fragmentation • performs independent of instrument settings • enables optimal selection of search mass tolerance for high mass accuracy experiments • is open source and thus can be tailored to individual needs • incorporates a SVM-based charge detection algorithm for analyzing low resolution tandem MS spectra • creates multiple output data formats (.dta, .MGF) • handles .RAW files and .mzXML formats • compatible with SEQUEST, MASCOT, X!Tandem
Revised: October 14, 2015 |
Published: April 1, 2008
Citation
Mayampurath A.M., N. Jaitly, S.O. Purvine, M.E. Monroe, K.J. Auberry, J.N. Adkins, and R.D. Smith. 2008.DeconMSn: A Software Tool for accurate parent ion monoisotopic mass determination for tandem mass spectra.Bioinformatics 24, no. 7:1021-1023.PNNL-SA-56275.doi:10.1093/bioinformatics/btn063