April 20, 2009
Book Chapter

Computational representation of biological systems

Abstract

Integration of large and diverse biological data sets is a daunting problem facing systems biology researchers. Exploring the complex issues of data validation, integration, and representation, we present a systematic approach for the management and analysis of large biological data sets based on data warehouses. Our system has been implemented in the Bioverse, a framework combining diverse protein information from a variety of knowledge areas such as molecular interactions, pathway localization, protein structure, and protein function.

Revised: June 12, 2009 | Published: April 20, 2009

Citation

Frazier Z., J.E. McDermott, M. Guerquin, and R. Samudrala. 2009. Computational representation of biological systems. In Computational Systems Biology, Methods in Molecular Biology. 535-550. Totowa, New Jersey:Humana Press. PNNL-SA-56401.