We report on the development and characterization of a new traveling wave-based Structure for Lossless Ion Manipulations (TW-SLIM) for ion mobility separations (IMS). The TW-SLIM module uses a parallel array of RF electrodes for ion confinement, spaced by an array of short DC electrodes to which a TW can be applied to drive ion motion. The ability of the TW-SLIM for efficient ion confinement, lossless ion transport, and ion mobility separations at different RF and TW parameters is reported. The TW-SLIM module is shown to allow transfers a wide mass range of ions (200-2500 Da) utilizing a confining RF waveform (1 MHz and 300 Vp-p), and low TW amplitudes (
Revised: May 2, 2016 |
Published: October 28, 2015
Citation
Hamid A.M., Y.M. Ibrahim, V. Garimella, I.K. Webb, L. Deng, T. Chen, and G.A. Anderson, et al. 2015.Characterization of Traveling Wave Ion Mobility Separations in Structures for Lossless Ion Manipulations.Analytical Chemistry 87, no. 22:11301-11308.PNNL-SA-111147.doi:10.1021/acs.analchem.5b02481