{[Cp*Ru(CO)2]2(? H)}+OTf – functions as a homogeneous catalyst precursor for hydrogenation of ketones to alcohols, with hydrogenations at 1 mol % catalyst loading at 90 °C under H2 (820 psi) proceeding to completion and providing >90% yields. Hydrogenation of methyl levulinate generates ?-valerolactone, presumably by ring-closing of the initially formed alcohol with the methyl ester. Experiments in neat Et2C=O show that the catalyst loading can be
Revised: April 5, 2010 |
Published: February 22, 2010
Citation
Fagan P.J., M.H. Voges, and R.M. Bullock. 2010.Catalytic Ionic Hydrogenation of Ketones by {[Cp*Ru(CO)2]2(? H)}+.Organometallics 29, no. 4:1045-1048.PNNL-SA-69639.doi:10.1021/om901005k