Proper spatial localization of EGFR signaling activated by autocrine ligands represents a critical factor in embryonic development as well as tissue organization and function, and ligand/receptor binding affinity is among the molecular and cellular properties suggested to play a role in governing this localization. Continued....
Revised: March 9, 2005 |
Published: August 8, 2002
Citation
Dewitt A., T. Iida, H. Lam, V. Hill, H.S. Wiley, and D.A. Lauffenburger. 2002.Affinity Regulates Spatial Range of EGF Receptor Autocrine Ligand Binding.Developmental Biology 250, no. 2:305-316.PNNL-SA-41390.