PNNL is heavily engaged in the development and use of mass spectrometry technology across its science, energy, and security missions, from fundamental research through mature operational capabilities.

The Molecular Observation Network is a national open science network designed to produce a comprehensive database of molecular and microstructural information on soil, water, microbial communities, and biogenic emissions.

The RD2C laboratory-directed research initiative seeks to develop resilient, adaptive, and intelligent sensing and control algorithms through the observational understanding and characterization of CPSs under adverse conditions.