The Data-Model Convergence (DMC) Initiative is a multidisciplinary effort to create the next generation of scientific computing capability through a software and hardware co-design methodology.

The Isotope Program at PNNL supports scientific advances in the production and use of radioisotopes for research, medicine, and industrial applications.

The RD2C laboratory-directed research initiative seeks to develop resilient, adaptive, and intelligent sensing and control algorithms through the observational understanding and characterization of CPSs under adverse conditions.