The Ion Dynamics in Radioactive Environments and Materials (IDREAM) Energy Frontier Research Center (EFRC) conducts fundamental science to support innovations in retrieving and processing high-level radioactive waste.

The Pacific Northwest Center for Cryo-EM electron microscopy is a user facility operated jointly by PNNL and Oregon Health & Science University.

The RD2C laboratory-directed research initiative seeks to develop resilient, adaptive, and intelligent sensing and control algorithms through the observational understanding and characterization of CPSs under adverse conditions.