The Pacific Northwest Center for Cryo-EM (PNCC) is a national user facility for cryo-electron microscopy that is jointly operated by Oregon Health & Sciences University (OHSU) and Pacific Northwest National Laboratory (PNNL). Funding is provided by the National Institutes of Health Common Fund (NIH).
PNCC provides new and experienced cryo-EM researchers with free access to state-of-the-art workflows for single particle analysis and electron tomography. The center also offers individual and group training to users related to:
Since 2019, PNCC has served over 800 unique users from 110 institutions, has collected over 12,000,000 cryo-EM movies, and has helped determine the structure of over 400 macromolecular complexes reported in peer-reviewed publications.
PNCC is one of the collaborative projects under the umbrella of the Pacific northwest bioMedical Innovation Co-laboratory (PMedlC).
PMedlC's mission is to use multidimensional omics and imaging data to improve understanding around disease and to inform customized treatment options for patients.