Lauren Charles, a chief data scientist at PNNL, showcased the vital research coming out of her program at The National Academies Forum workshop in Washington, D.C., January 15–16, 2025.

PNNL biodefense experts seek to identify, understand and mitigate the risks of biological pathogens—whether naturally occurring or intentionally created—so steps can be taken to prepare and respond.

Researchers will explore climate, pathogens and energy-efficient microelectronics using 3 million node hours on the nation’s supercomputers.

Research at PNNL and the University of Texas at El Paso are addressing computational challenges of thinking beyond the list and developing bioagent-agnostic signatures to assess threats.

Beyond melting ice and higher temperatures: On Earth Day, scientists consider how climate change will affect national security.

A new method to convert waste plastic to fuel and raw materials promises to help close the carbon cycle at mild temperature and with high yield.

Microbes that were previously frozen in soils are becoming more active. This study demonstrates the diverse RNA viral communities found in thawed permafrost.

Scientists can detect the virus that causes COVID-19 by using a bubble that spills its contents like a piñata when encountering the virus.

TransMED analyzes patient data from similar diseases across multiple sources to understand COVID-19 patient outcome risk factors.

The virus that causes COVID-19 takes over the body’s fat-processing system and boosts cellular triglycerides as it causes disease.

PNNL researchers develop software that uses geographical data to build a free, open-source grid reference system to provide a precise system to locate structures.

PNNL scientists publish paper and host workshops to share threat-agnostic vision for biodefense.

A study of Middle East Respiratory Syndrome has identified a compound that shows potential in easing the symptoms of coronavirus infections.

Mary Lancaster, epidemiologist and data scientist, co-authored a chapter on cyberbiosecurity for the NATO Science for Peace and Security book series.

PNNL researchers can make methane from captured CO2 and renewably sourced hydrogen, offering a path toward cheaper synthetic natural gas.

A Q&A with Lauren Charles, veterinarian and PNNL data scientist, on zoonotic diseases and the role biosurveillance plays in mitigating the growing threat to global health.

PNNL teamed with academia and industry to develop a novel zero-emission methane pyrolysis process that produces both hydrogen and high-value carbon solids suitable for an array of manufacturing applications.

PNNL’s newest solvent captures carbon dioxide from power plants for as little as $47.10 per metric ton, marking a significant milestone in the journey to lower the cost of carbon capture.

PNNL researchers have developed a new class of chemistry focused on carbon capture technology and made incremental strides in driving down costs.

In a new review, PNNL researchers outline how to convert stranded biomass to sustainable fuel using electrochemical reduction reactions in mini-refineries powered by renewable energy.