The Coastal Observations, Mechanisms, and Predictions Across Systems and Scales: Field, Measurements, and Experiments project established a network of observational field sites across Chesapeake Bay and western Lake Erie.

Due to their inherent variability and complexity over space and time, scientists are challenged to understand the complex interactions among soil, vegetation, and water along coastal terrestrial-aquatic interfaces.

This study characterized above- and below-ground properties to explore the spatial heterogeneity of the terrestrial aquatic interface ecosystem within the Chesapeake Bay area and evaluate the major drivers of soil respiration.

Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.

A new study led by PNNL researcher TC Chakraborty provides some answers about how irrigated agricultural land near cities affects urban heat stress.

Researchers at PNNL are pursuing new approaches to understand, predict and control the phenome—the collection of biological traits within an organism shaped by its genes and interactions with the environment.

Armed with some of the world’s most advanced instrumentation, researchers at PNNL are working to analyze huge amounts of data and uncover hidden biological connections.

Three PNNL technologies have been declared winners of 2025 Federal Laboratory Consortium Awards, named for a program that recognizes federal laboratories and their industry partners for outstanding technology transfer achievements.

This week at AAAS, PNNL scientists discuss phenomics and the factors that influence DNA instructions to bring about the world around us.

CACTUS provides AI-powered cheminformatics for autonomous science.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

Scientists are using artificial intelligence and powerful computing to sculpt new molecules in an effort to treat disease.

PNNL chief data scientist Lauren Charles participated in a science-focused panel linked to the 79th session of the United Nations General Assembly.

Controlling the nanostructure of silk fibroin—a protein found in silk—is a key step toward designing and fabricating electronics that leverage the material’s promising mechanical, optical and biocompatible properties.

Scientists are developing ways to detect previously unseen forms of fentanyl as well as other synthetic opioids known as nitazenes.

This study evaluated the sensitivity of multiple geophysical methods to measure and evaluate the spatiotemporal variability of select soil properties across terrestrial–aquatic interfaces.

Researchers integrated field measurements, lab experiments, and model simulations to study oxygen consumption dynamics in soils along a coastal gradient.

This research explores how changes in groundwater levels affect the chemistry of underground water, especially in areas where land meets water, like wetlands.

Lauren Charles, a chief data scientist at PNNL, has been named an affiliate member of Global One Health Academy at North Carolina State University.