Armed with some of the world’s most advanced instrumentation, researchers at PNNL are working to analyze huge amounts of data and uncover hidden biological connections.

Scientists have learned more about how drug resistance develops in patients with acute myeloid leukemia and how the process might be slowed.

Spatial proteomics enables researchers to link protein measurements to features in the image of a tissue sample, which are lost using standard approaches.

PNNL’s Nick Ward has been honored with the American Geophysical Union’s Thomas Hilker Early Career Award.

The diversity and function of organic matter in rivers at a large scale are influenced by factors, such as the types of vegetation covering the land, the energy characteristics, and the breakdown potential of the molecules.

A detailed snapshot of proteins by PNNL scientists marks a big step toward a diagnostic blood test for a deadly form of liver disease.

PNNL Biomedical Scientist Geremy Clair has taken on new roles as an editor for two journals; Frontiers In Cellular And Infection Microbiology and Frontiers In Molecular Biosciences.

New research findings published in Science Advances (November 2022), help explain the progression of Alzheimer-related dementia in each patient. The findings outline a biological classification system that predicts disease severity.

PNNL chemist Ying Zhu was honored as one of the top 40 researchers under the age of 40 in analytical science by The Analytical Scientist.

Diefenderfer, Earth scientist who focuses on coastal ecosystems at PNNL, recently published “Ten Years of Gulf Coast Ecosystem Restoration Projects Since the Deepwater Horizon Oil Spill,” a cover article.

ICON science is a Department of Energy-developed framework to enhance scientific outcomes via more intentional design of research efforts across all domains of science.

An analysis of land use in watersheds that supply drinking water to over a hundred United States cities identified a wide range of exposure to potential contamination.

PNNL scientists are taking part in a Department of Energy climate science field campaign in the Rocky Mountains of Colorado.

Governor Inslee announced the appointment of Karin Rodland to the Board of Directors of the Andy Hill Cancer Research Endowment Fund.

COMPASS points to understanding nature’s transition zones—areas that can be dry land at times and under water at others.

The nested nanoPOTS chip is the next generation of technology developed at PNNL to prepare single cells for proteomics.

A new microbial community model reveals previous exposure to hydrologic variation influences a species’ specialized biogeochemical functions.

Detailed characterization of molecules in, under, and along the Columbia River reveal potential mechanisms for biogeochemical cycling.

Integrating hydrogeology and biogeochemistry are required to model the dynamics of geochemical processes occurring in river corridor zones where groundwater and surface water mix.

Theoretical analysis reveals flow variations that happen over longer time periods affect a plume’s spread and center of mass.