Integrating experiments and modeling show how a fungal exudate-inspired substrate mixture elicits an emergent growth phenotype and metabolic responses in Pseudomonas putida.

Uncovered how the choice of carbon source influences the stress tolerance, redox balance, and regulatory responses of yeast, which can help provide resilience against scale-up challenges.

Five PNNL innovations earned 2026 R&D 100 Awards for advances in biotechnology, manufacturing, critical minerals, and nuclear security.

A team from PNNL joined the Department of Homeland Security Science and Technology Directorate and first responders from across the country to evaluate commercially available unmanned ground vehicles for emergency response.

Study shows the advantages of top-town proteomics for characterizing histones.

A microbial community expresses a phenotype of interest ~20 percent higher than the sum of each member species.

Structural proteomics reveal how cyanobacteria adapt to changing light.

Secretary Wright visited PNNL's campus in Richland, Washington, late last year to meet with innovators in chemistry, biology, computing, and more.

Researchers use multiomics to confirm role of lipid synthesis during infection, leading to model of how to restrict virus replication.

PNNL researchers Daniel Deng and Yehia Ibrahim join the 2025 class of National Academy of Inventors Fellows.

Capturing protein structural changes in host cells exposes vulnerabilities exploited by viruses to hijack cellular machinery.

From developing new energy storage materials to revealing patterns of Earth’s complex systems, studies led by PNNL researchers are recognized for their innovation and influence.

PNNL researchers developed a new computational workflow to study day-to-night gene expression dynamics of cyanobacterium in real time.

Understanding molecular modifications of proteins in the red yeast could help scientists re-engineer the organism’s phenotype.

Lakes are important sentinels of climate change and contribute significantly to the emissions of the second most important greenhouse gas—methane.

The rate of conversion of cloud droplets to precipitation, known as the autoconversion rate, remains a major source of uncertainty in characterizing aerosol’s cloud lifetime effects and precipitation in global and regional models.

Two new publications provide emergency response agencies with critical insights into commercially available unmanned ground vehicles used for hazardous materials response.

To assess the impact of observation period and gauge location, model parameters were learned on scenarios using different chunks of streamflow observations.

Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.

The Wildfire Mitigation Plan Database was built to support electric utilities, state governments, policymakers, and regulators in understanding and improving wildfire risk and resilience strategies.