PNNL researchers developed a new computational workflow to study day-to-night gene expression dynamics of cyanobacterium in real time.

Understanding molecular modifications of proteins in the red yeast could help scientists re-engineer the organism’s phenotype.

Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.

Flexible, high-throughput proteomics approach identifies protein modifications related to pancreatic stress and insulin production.

Scientists uncover how cyanobacteria's circadian cycle controls carbon and energy metabolism, increasing carbon dioxide-to-bioproducts yields.

Scientists map how transitions from day to night control gene regulatory networks in cyanobacteria, revealing key orchestrators of metabolic switching.

Researchers developed a robust, cost-effective, and easy-to-use cap-based technique for spatial proteome mapping, addressing the lack of accessible proteomics technologies for studying tissue heterogeneity and microenvironments.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

Computing and artificial intelligence aid scientists who seek to understand function-driven design and control of biological systems.

Capstone engineering projects deliver equipment to improve accuracy of chemistry lab elutions and enhance training to safeguard critical infrastructure.

The new PTM-Psi workflow opens the door for uncovering molecular insights within proteomics datasets.

Scientists developed a process (or pipeline) that combined molecular probes—a specific chemical that binds to microbes carrying out a particular function—with a method that isolated these cells from their complex community.

Scientists screen for nanobodies that recognize wild type and mutant functional proteins to develop a framework to disrupt protein interactions that can cause disease.

Advanced proteomic analysis tools dig deep into human blood plasma to understand the molecular nature of advanced alcoholic disease.

PNNL research, featured on the cover of two science journals, describes advancements in using Raman spectrometry for Hanford Site nuclear waste remediation.

PNNL experts in nuclear forensics helped lead laboratories around the world through a rigorous test involving nuclear materials.