Early life exposure to polycyclic aromatic hydrocarbons (PAHs), found in smoke, has been linked to developmental problems. To study the impacts of these pollutants, PAH metabolism in infants and adults were compared.

PMedIC, the PNNL and OHSU joint research collaboration, contributes to student success and impact in biomedicine.

Spatial proteomics enables researchers to link protein measurements to features in the image of a tissue sample, which are lost using standard approaches.

Mandy Mahoney, director of the DOE Building Technologies Office, visited PNNL in late November. One key agenda item involved meeting with staff for a discussion of effective equity and justice integration in buildings-related research.

Scientists screen for nanobodies that recognize wild type and mutant functional proteins to develop a framework to disrupt protein interactions that can cause disease.

Staff at PNNL recently completed a report highlighting commercial products enabled through projects funded by the Department of Energy’s Building Technologies Office.

Silicone wristbands could be more convenient option for collecting exposure data.

Study highlights microbiome’s role in regulating xenobiotic metabolism.

Simulations reveal advantages of using new model vs. allometric scaling for risk assessment.

Exposure to polycyclic aromatic hydrocarbons found at Superfund Sites induces enzymes in dose- and time-dependent patterns in mice.