Researchers use multiomics to confirm role of lipid synthesis during infection, leading to model of how to restrict virus replication.

PNNL researchers Daniel Deng and Yehia Ibrahim join the 2025 class of National Academy of Inventors Fellows.

Capturing protein structural changes in host cells exposes vulnerabilities exploited by viruses to hijack cellular machinery.

PNNL researchers developed a new computational workflow to study day-to-night gene expression dynamics of cyanobacterium in real time.

Understanding molecular modifications of proteins in the red yeast could help scientists re-engineer the organism’s phenotype.

Continued studies will deepen scientists’ understanding of virus-host interactions at the molecular level and also pave the way for developing better drugs to fight emerging viruses.

Flexible, high-throughput proteomics approach identifies protein modifications related to pancreatic stress and insulin production.

Scientists uncover how cyanobacteria's circadian cycle controls carbon and energy metabolism, increasing carbon dioxide-to-bioproducts yields.

Scientists map how transitions from day to night control gene regulatory networks in cyanobacteria, revealing key orchestrators of metabolic switching.

PNNL's accomplishments in FY 2024 help address the remaining challenges the wind industry faces.

PNNL scientists use proteomics to unveil how high-density lipoproteins protect against cholesterol accumulation in the artery wall.

Computing and artificial intelligence aid scientists who seek to understand function-driven design and control of biological systems.

PNNL researchers are exploring the kinds of flicker waveforms that the eye and brain can detect, seeking to understand the different visual and non-visual effects that result.

With the launch of a large research barge, PNNL and collaborators took another significant step to improve offshore wind forecasting that will lower risk and cost associated with offshore wind energy development.

GUV can reduce transmission of airborne disease while reducing energy use and carbon emissions. But fulfilling that promise depends on having accurate and verifiable performance data.

The nation is closer to its offshore wind energy goals than ever before, but better wind forecasting is still needed. To address this challenge, PNNL and collaborators are charting a new course with help from novel technology.

The new PTM-Psi workflow opens the door for uncovering molecular insights within proteomics datasets.

Mandy Mahoney, director of the DOE Building Technologies Office, visited PNNL in late November. One key agenda item involved meeting with staff for a discussion of effective equity and justice integration in buildings-related research.