PNNL

Pacific Northwest National Laboratory (PNNL) researchers will be presenting and leading discussions during the Chemical and Biological Defense Science and Technology (CBD S&T) Conference, December 2–5, 2024, in Fort Lauderdale, Florida. The event brings together leaders from around the world in the chemical and biological defense community to share the latest insights on current and future chemical-biological threats.

The conference is organized by the Chemical and Biological Technologies Department within the Defense Threat Reduction Agency (DTRA).

Featured PNNL Talks

Tuesday, December 3

Canary: An AI-Powered Software Toolbox for the Identification and Prediction of 21st Century Chemical Threats

Session: 10:50–11:30 a.m. EST | Location: Grand Ballroom D/F

PNNL Speaker: Kate Schultz

Summary: Decision-makers need precise, actionable risk data to guide chemical and biological defense strategies. Traditional methods can’t keep up with emerging chemical threats, but AI/ML tools offer faster, cost-effective alternatives. A new AI-based platform, Canary, leverages an extensive molecular database to predict toxicity, aiding rapid screening and prioritization across chemical hazards. READ MORE.

Wednesday, December 4

NCAP-AI: AI/ML Augmented Potentials for ncAA Peptide Design

Session: 11:10–11:50 a.m. EST | Location: Grand Ballroom D/F

PNNL Speaker: Richard Overstreet

Summary: Non-canonical amino acids (ncAAs) open new possibilities for protein design. NCAP-AI software leverages AI and physical modeling to efficiently predict ncAA mutations' stability and function. By screening StigA15 peptide mutations, NCAP-AI identifies promising antimicrobial variants against drug-resistant bacteria, streamlining the design of next-generation therapeutics. READ MORE.

Featured PNNL Posters

Tuesday, December 3

Finch: An AI-Powered Toolbox for the Prediction of Chemical Mixture's Physiological Function and Hazard Profile

Location: Hall A | Booth #15

PNNL Presenter: Mark Maupin

Detection of Enzymatic Activity using Commercial-off-the-Shelf (COTS) Nanopore Sequencing-based Instrument

Location: Hall A | Booth #455

PNNL Presenter: Jennifer Mobberley

KESTREL: Knowledge Extraction for Strategic Threat Response using Evidence from the Literature

Location: Hall A | Booth #107

PNNL Presenter: Lindsey Anderson

Wednesday, December 4

Computational Redesign of Monomeric Native Protein using Non-canonical Amino Acids

Location: Hall A | Booth #2

PNNL Presenter: Doo Nam Kim

Profiling Healthy Human Breath using Artificial Intelligence

Location: Hall A | Booth #24

PNNL Presenter: Lisa Bramer

An AI-Driven Security Platform for Threat Awareness and Decision Support

Location: Hall A | Booth #382

PNNL Presenter: Samantha Erwin

Discovery of Non-Canonical Protein Targets of Fentanyl across Tissues from Animal Models and Humans using Photoaffinity Fentanyl Probes

Location: Hall A | Booth #476

PNNL Presenter: Vivian Lin

Identification and Validation of Protein-Chemical Threat Interactions from Activity-Based Protein Profiling (ABPP) Data

Location: Hall A | Booth #518

PNNL Presenter: John Cort
 

Careers at PNNL

If you’re interested in working at PNNL, we encourage you to take a look at our careers page!